Desang diabetes magazine, diabetes news, beta cells, Abbott FreeStyle LIbre 3, FSL3

4

NEWS

Aussie rules

All 130,000 Australians with Type

1 diabetes will now get access to

subsidised continuous glucose

monitoring (CGM) devices under

the newly-elected Australian Prime

Minister Anthony Albanese's National

Diabetes Services Scheme (NDSS).

All Australians over the age of

21 with Type 1 diabetes will be able

to access CGM products through

their pharmacy, with a co-payment

equivalent to AUS$390 per year.

Children and young adults under 21

with Type 1 diabetes, concession card

holders with Type 1 diabetes, and

people with Type 1 diabetes who are

pregnant, post-pregnancy or trying

to become pregnant, will continue to

receive these products free of charge

through the NDSS,

The Albanese Government

is also expanding the eligibility

criteria for its separate Insulin Pump

Program, providing an additional

35 fully subsidised insulin pumps

per year for young adults aged 18

to 21 with Type 1 diabetes from

financially disadvantaged families,

when these were previously limited

only to children up to the age of 18.

Minister Butler commented, "The

Albanese Government is delivering

our election commitment to support

all Australians living with Type 1

diabetes to get access to subsidised

CGM products."

ADA supports

INSULIN Act

The American Diabetes

Association(ADA), has applauded

U.S. Senators Jeanne Shaheen (DNH) and Susan

Collins (R-ME) for

recently introducing legislation

which aims to make insulin

more affordable for millions of

Americans with diabetes.

Insulin costs 10 times more

in the U.S. than anywhere else in

the world, and as many as 1 in 4

US insulin users report rationing

their insulin - skipping doses or

taking less than they need, putting

themselves at risk for serious

complications. With the rising

cost of insulin now being seen

as unsustainable, the ADA has

long advocated for reform of the

prescription drug rebate system

that inflates the cost of insulin.

The bipartisan Improving

Needed Safeguards for Users of

Lifesaving Insulin Now (INSULIN)

Act includes important reforms

to reduce the price of insulin by

incentivising lower list prices and

including limits on out-of-pocket

costs for patients.

"We applaud the commitment

of Senators Shaheen and Collins to

finally make insulin affordable at a

national level and we thank them

for their leadership in legislation

that includes important reforms

to reduce the price of insulin by

incentivizing lower list prices and

include limits on out-of-pocket

costs," said Lisa Murdock, chief

advocacy officer of the American

Diabetes Association. "Critically,

these provisions would help both

the insured and the uninsured

patient communities."

Beta cells to blame?

New research at the University

of Chicago claims the causes of

Type 1 diabetes focus on an autoimmune response,

in which the

immune system shatters the islets of

Langerhans, which help to control

the amount of glucose in the body.

According to findings published

in Cell Reports, the researchers

used genetic tools to knock out

a gene called Alox15 in mice that

were genetically predisposed to

developing type 1 diabetes. This

gene produces an enzyme called

12/15-Lipoxygenase, which is known

to produce inflammation in beta

cells. Deleting the Alox15 gene in

these mice preserved their amount

of beta cells, reduced the number of

immune T cells infiltrating the islets

and prevented Type 1 diabetes from

developing. These mice also showed

increased expression of the gene that

suppresses autoimmunity.

"The immune system doesn't

just decide one day that it's going to

attack your beta cells. Our thinking

was that the beta cell itself has

somehow fundamentally altered

itself to invite that immunity," said

senior author Raghavendra Mirmira,

MD, PhD, Professor of Medicine and

Director of the Diabetes Translational

Research Center at UChicago. "When

we got rid of this gene, the beta cells

no longer signalled to the immune

system and the immune onslaught

was completely suppressed. There

is a complex dialogue between beta

cells and immune cells, and if you

intervene in that dialogue, you can

prevent diabetes."

The study also revealed that

new medications could block the

immune system from destroying beta

cells and prevent Type 1 diabetes

from developing in at-risk or early

onset patients. The researchers

tested a drug that inhibits the

12/15-Lipoxygenase enzyme on

human beta cells and saw that the

drug, called ML355, could interrupt

the autoimmune response and

prevent diabetes from developing.

Ideally, it would be given to patients

who are at high risk because of

family history and show early signs

of developing Type 1 diabetes, or

shortly after diagnosis. Mirmira and

his team are taking the first steps to

start clinical trials to test a possible

treatment using ML355.

Index

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  7. Dexcom G6 CGM, continuous glucose monitoring
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  9. Medtronic Guardian Connect CGM sensor for diabetes
  10. diabetes news, diabetes research news, diabetes information, diabetes kit, diabetes technology
  11. Diabetes UK
  12. ViaCyte being bought by Vertex to advance cure for type 1 diabetes.
  13. Medtronic MiniMed 780G System Automated for an easier way to stabilise glucose levels
  14. ViaCyte being bought by Vertex to advance cure for type 1 diabetes.
  15. JDRF UK, DigiBete solutions for children and young adults with Type 1 diabetes.
  16. Hallmark Care Homes, DUET Diabetes, National Advisory Panel on Care Home Guidance, Professor Alan Si
  17. Hallmark Care Homes, DUET Diabetes, National Advisory Panel on Care Home Guidance, Professor Alan Si
  18. Problems facing people with diabetes in high weather temperatures from Diabetes UK.
  19. Ascensia GloucoContro diabetes blood test result sharing software
  20. Sigi Insulin Management System, AMP Medical, Sigi insulin pump.
  21. Desang diabetes, Inside Diabetes guides
  22. donation to UK diabetes charities JDRF and Diabetes UK.
  23. donation to UK diabetes charities JDRF and Diabetes UK.
  24. OCDEM (Oxford Centre for Diabetes, Endocrinology and Metabolism and the Oxford DRWF Human Islet Isol
  25. OCDEM (Oxford Centre for Diabetes, Endocrinology and Metabolism and the Oxford DRWF Human Islet Isol
  26. OCDEM (Oxford Centre for Diabetes, Endocrinology and Metabolism and the Oxford DRWF Human Islet Isol
  27. Insulet Omnipod DASH insulin pump with insulin pods, podders, Omnipod DASH Personal Diabetes Manager
  28. OCDEM (Oxford Centre for Diabetes, Endocrinology and Metabolism and the Oxford DRWF Human Islet Isol
  29. DRWF wellness days and events
  30. Desang Diabetes Magazine, free diabetes magazine, living with diabetes
  31. Desang Diabetes Magazine, free diabetes magazine, living with diabetes
  32. diabetes food news, diabetic diet, counting carbohydrates
  33. Diabetes technology education from Diabetes Technology Network DTN
  34. diabetes food news, diabetic diet, counting carbohydrates
  35. Medtrum Touchcare Nano Patch Pump and CGM
  36. Page 0036
  37. Abbott Freestyle Libre 2, Flash Glucose Monitoring, FSL2
  38. Desang Diabetes Magazine, Making Carbs Count, carbohydrate counting for diabetes
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  40. Desang Diabetes Magazine, Making Carbs Count, carbohydrate counting for diabetes, anchovies and diab
  41. Desang diabetes kitbags, bag for diabetes kit
  42. Desang Diabetes Magazine, free diabetes magazine, living with diabetes

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