OCDEM (Oxford Centre for Diabetes, Endocrinology and Metabolism and the Oxford DRWF Human Islet Isol

28

LIVING

for life-long immunosuppression

(anti-rejection drugs) following

islet transplantation.

Since the launch of the Islet

Isolation Facility in 2006, DRWF

has continued to provide invaluable

financial support to its key personnel.

The Oxford isolation team comprises

up to 12 members of staff, all of

whom are engaged in islet isolation

and in islet isolation research.

Louise Stile joined DRWF Islet

Facility as Co-ordinator and personal

assistant to Professor Johnson, who

comments, "Louise is the lynchpin

that keeps the whole DRWF Oxford

Human Islet Isolation Facility and the

Oxford Islet Isolation team running."

Rebecca Spiers, joined the human

islet isolation facility in 2014 and

in 2021 became the DRWF Facility

Manager. Anju Abraham, who joined

the facility in 2015 as a research

technician, became the DRWF

Deputy Facility Manager in February

of 2022.

DRWF has made a significant

commitment to islet cell research

Investing in the future

The Oxford Centre for Diabetes, Endocrinology

and Metabolism (OCDEM) building at The Churchill

Hospital, part of the Radcliffe Department of Medicine

at Oxford University, was designed to accommodate

basic research and teaching facilities, a ward for

clinical trials of new diabetes drugs and treatments,

and the regular diabetes ward and clinics. The building

design means that all scientists working in OCDEM

have to walk to their offices or laboratories past the

central patient waiting area to be reminded why they

are doing the work and of the urgent need for them to

find a cure.

When the DRWF funding was confirmed in 2004,

unused space in the undercroft of this new building

was identified as being available for the isolation unit to

be housed. DRWF donated £1.2m and the lab was built

in 2005 with the state-of-the-art facilities officially

opening in January 2006.

Professor Johnson has been Director of the Oxford

Islet Transplant Programme since 2003. He performed

his first islet isolation procedure in 1989. He says, "Islet

isolation remains challenging as each donor is different

and the techniques we use are not like following a

rigid recipe. Successful islet isolation relies heavily on

experience and I am so privileged to be working in a

state-of-the-art Facility generously funded by DRWF

with a team of highly experienced and dedicated

individuals.' Islet transplantation has actually been

around for many years. During the 1990s, almost 500

islet transplants took place. However, only about 11%

of recipients achieved insulin-independence. In 2000,

a new clinical protocol was developed (the Edmonton

Protocol) which helped transform islet transplantation

to a treatment with much higher success. Today it is an

option for those who meet the right criteria.

and transplant both in the UK

and around the world. It is hoped

there will be more refinements and

improvements to the processes to

enable it to become more widely

available as a treatment option in

future years.

Professor Johnson concludes,

"The Oxford DRWF Human Islet

Isolation Facility is to become

one of the premier islet isolation

establishments in the world. It is

central to the success of the UK

Clinical Islet Transplant Programme.

Members of the Oxford team

are leaders in the field of human

islet isolation and islet transplant

research. None of these things would

have been possible without the

generosity of DRWF."

Sarah Tutton, Chief Executive

of DRWF in the UK adds, "Donors

to the charity can see tangible and

fruitful outcomes of their generous

efforts though the results being seen

at the isolation facility which they

have funded."

www.drwf.org.uk

Donors to the

charity can see

tangible and

fruitful outcomes

of their generous

efforts

~ Sarah Tutton

Index

  1. Desang diabetes magazine, Making Carbs Count, Diabetes KIT, non-invasive glucose testing, OCDEM, Sig
  2. Desang diabetes, magazine diabetes information, Sue Marshall diabetes
  3. Desang diabetes, magazine diabetes information, Sue Marshall diabetes
  4. Desang diabetes magazine, diabetes news, beta cells, Abbott FreeStyle LIbre 3, FSL3
  5. insulin pump, Dana i system, artificial pancreas, Advanced Therapeutics UK, CamAPS FX, Dexcom G6
  6. diabetes news, diabetes research news, diabetes information, diabetes kit, diabetes technology, JDRF
  7. Dexcom G6 CGM, continuous glucose monitoring
  8. Dexcom G6 CGM, continuous glucose monitoring
  9. Medtronic Guardian Connect CGM sensor for diabetes
  10. diabetes news, diabetes research news, diabetes information, diabetes kit, diabetes technology
  11. Diabetes UK
  12. ViaCyte being bought by Vertex to advance cure for type 1 diabetes.
  13. Medtronic MiniMed 780G System Automated for an easier way to stabilise glucose levels
  14. ViaCyte being bought by Vertex to advance cure for type 1 diabetes.
  15. JDRF UK, DigiBete solutions for children and young adults with Type 1 diabetes.
  16. Hallmark Care Homes, DUET Diabetes, National Advisory Panel on Care Home Guidance, Professor Alan Si
  17. Hallmark Care Homes, DUET Diabetes, National Advisory Panel on Care Home Guidance, Professor Alan Si
  18. Problems facing people with diabetes in high weather temperatures from Diabetes UK.
  19. Ascensia GloucoContro diabetes blood test result sharing software
  20. Sigi Insulin Management System, AMP Medical, Sigi insulin pump.
  21. Desang diabetes, Inside Diabetes guides
  22. donation to UK diabetes charities JDRF and Diabetes UK.
  23. donation to UK diabetes charities JDRF and Diabetes UK.
  24. OCDEM (Oxford Centre for Diabetes, Endocrinology and Metabolism and the Oxford DRWF Human Islet Isol
  25. OCDEM (Oxford Centre for Diabetes, Endocrinology and Metabolism and the Oxford DRWF Human Islet Isol
  26. OCDEM (Oxford Centre for Diabetes, Endocrinology and Metabolism and the Oxford DRWF Human Islet Isol
  27. Insulet Omnipod DASH insulin pump with insulin pods, podders, Omnipod DASH Personal Diabetes Manager
  28. OCDEM (Oxford Centre for Diabetes, Endocrinology and Metabolism and the Oxford DRWF Human Islet Isol
  29. DRWF wellness days and events
  30. Desang Diabetes Magazine, free diabetes magazine, living with diabetes
  31. Desang Diabetes Magazine, free diabetes magazine, living with diabetes
  32. diabetes food news, diabetic diet, counting carbohydrates
  33. Diabetes technology education from Diabetes Technology Network DTN
  34. diabetes food news, diabetic diet, counting carbohydrates
  35. Medtrum Touchcare Nano Patch Pump and CGM
  36. Page 0036
  37. Abbott Freestyle Libre 2, Flash Glucose Monitoring, FSL2
  38. Desang Diabetes Magazine, Making Carbs Count, carbohydrate counting for diabetes
  39. Desang Diabetes Magazine, Making Carbs Count, carbohydrate counting for diabetes
  40. Desang Diabetes Magazine, Making Carbs Count, carbohydrate counting for diabetes, anchovies and diab
  41. Desang diabetes kitbags, bag for diabetes kit
  42. Desang Diabetes Magazine, free diabetes magazine, living with diabetes

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