Diabetes medications, Type 1 diabetes, Type 2 diabetes

LIVINGLIVING

WELL TREATED

New diabetes treatments can be hard to keep track of. Here

we take a look at some of the newer treatments and trials for

diabetes. By Angela Coffey.

B

eing armed with the

basic facts about

new and potential

treatments is a great

way to keep track of

what could be suitable for you and to

ask about them at your next diabetes

appointment. Of course, the decision to

start any new treatments ultimately lies

with your doctor, but there's never any

harm in finding out more and having a

discussion about it - particularly if your

current treatment isn't giving you the

best control. From new oral medications

to supplement insulin therapy for Type 1

diabetes, to a new once-weekly injection

to treat Type 2, here are some of the new

medications on the market, as well as

current trials that could be ones to watch.

Treatments for Type 1

SGLT2 inhibitors

While SGLT2 inhibitors are a group of

medications mainly used to treat Type 2

diabetes, there are now two types of the

pill that have been approved for people

with Type 1 who have a BMI of more than

27 kg/m2 when insulin on its own isn't

providing adequate blood sugar control.

Taken once daily, Forxiga

(dapagliflozin), developed by Bristol-Myers

Squibb in partnership with AstraZeneca,

and Zynquista (sotagliflozin), developed

by Sanofi and Lexicon, both work by

reducing the amount of glucose absorbed

in the kidneys so that it's passed out in the

urine and, as a result, reduces the amount

of glucose in the blood.

Taken alongside insulin, SGLT

inhibitors can make a huge difference for

some people with Type 1 - increasing

time in range and reducing insulin doses,

HbA1c and blood pressure. And, by

passing glucose out of the body, the

accompanying calories are also excreted,

which results in weight loss - an additional

benefit. It's important, though, to stick to

a healthy diet and take regular exercise.

However, there's an increased risk of

diabetic ketoacidosis (DKA), and people

taking the treatment will need to carefully

monitor ketones and be fully aware of the

symptoms.

ADO09

Currently in trials, ADO09, developed

by Adocia, is a new co-formulation of

pramlintide (a synthetic form of hormone

amylin) and rapid-acting insulin for people

with Type 1 diabetes.

Intended to improve post-mealtime

blood sugar control, in Phase 1 trials

ADO09 was shown to have an 85%

decrease in blood sugar excursion over

the first two hours after a meal, when

compared to the rapid-acting insulin

Humalog on its own. ADO09 also showed

similar blood sugar control over the first

two hours after a meal compared to

continued over

Index

  1. Desang diabetes magazine diabetes information
  2. Dexcom CGM, continuous glucose monitoring
  3. Desang diabetes magazine diabetes information, Sue Marshall
  4. Desang diabetes magazine diabetes news
  5. Desang diabetes magazine diabetes news
  6. Desang diabetes magazine diabetes news
  7. Page 0007
  8. Page 0008
  9. Medtronic Minimed 670G hybrid closed loop insulin pump
  10. Connected insulin pens, Novo Nordisk, Timesulin, Big Foot Biomedical, InsulCheck
  11. Connected insulin pens, Novo Nordisk, Timesulin, Big Foot Biomedical, InsulCheck
  12. Desang diabetes magazine diabetes diet
  13. Desang diabetes kitbags
  14. Page 0014
  15. HbA1c home test, A1C now, BHR Pharmaceuticals Ltd, home use A1C test, home use HbA1c test
  16. Page 0016
  17. Page 0017
  18. JDRF stem cell encapsulation
  19. Omnipod Insulet insulin pump with insulin pods, podders
  20. Desang Diabetes Magazine, free diabetes magazine, living with diabetes
  21. Desang Diabetes Magazine, free diabetes magazine, living with diabetes
  22. Blood test meters, nothing beats a blood test, CGM
  23. Blood test meters, nothing beats a blood test, CGM
  24. Ascensia Contour Next One Diabetes blood test meters
  25. ia Contour Next One Diabetes blood test meters
  26. Blood test meters, blood glucose meters, Kinetik Wellbeing, Ypsomed mylife Unio
  27. Ypsomed MyLife Diabetes care blood glucose monitoring systems
  28. Diabetes medications, Type 1 diabetes, Type 2 diabetes
  29. Diabetes Research and Wellness Foundation, DRWF Wellness Days
  30. Diabetes medications, Type 1 diabetes, Type 2 diabetes
  31. Ascensia Contour Next One Diabetes blood test meters
  32. Kit that's coming soon MyGrams smartphone scales
  33. Kit that's coming soon MyGrams smartphone scales
  34. Making Carbs count: Counting carbs for the diabetic diet
  35. Making Carbs Count teff
  36. Making Carbs Count teff
  37. Accu-Chek Insight insulin pump for Animas users
  38. Desang Diabetes Magazine, free diabetes magazine, living with diabetes

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