Desang diabetes magazine, diabetes news

NEWS

EXERCISE KEY TO VISION

Exercise can slow or prevent the

development of macular degeneration

and may benefit other common causes of

vision loss, such as glaucoma and diabetic

retinopathy, new research suggests.

The study from the University of Virginia

School of Medicine (UVA) found that

exercise reduced the harmful overgrowth

of blood vessels in the eyes of lab mice by

up to 45%. This tangle of blood vessels is

a key contributor to macular degeneration

and several other eye diseases.

The study represents the first

experimental evidence showing that

exercise can reduce the severity of

macular degeneration, a leading cause

of vision loss, the scientists report. The

research found that the bar for receiving

the benefits from exercise was relatively

low - more exercise didn't mean more

benefit. "Mice are kind of like people in

that they will do a spectrum of exercise.

As long as they had a wheel and ran

on it, there was a benefit," Gelfand, of

In a report written for JDRF by Brian

Herrick, Tandem Diabetes has gained

FDA clearance of an expanded paediatric

indication for the Tandem t:slim X2 insulin

pump with Control-IQ technology in

children ages six and older. The device was

initially only authorized for use in people

14 and older. Simply put: more people

now have access to this life-changing

technology. The data for the clearance

came from the International Diabetes

Closed Loop Protocol-5 (DCLP5), a sixmonth

study of children ages 6-13. This

study was funded by the NIH's National

Institute of Diabetes and Digestive and

Kidney Diseases (NIDDK) with funds from

the Special Diabetes Program (SDP), for

which JDRF is the primary advocate. The

results were definitive: Control-IQ helps

children with T1D do better.

Children in the six-month trial

experienced an increase in time in range

overall (67% for those on Control-IQ

compared to 53% in the control group),

and increased time in range overnight

(80% for those on Control-IQ™ compared

to 54% in the control group). This will help

a lot of children (and their parents) sleep

better at night.

When Control-IQ first received FDA

authorization for people 14 and older on

December 2019 it was the first algorithm

authorized as an interoperable automated

glycaemic controller, meaning that the

algorithm could be a component of an

open protocol, or interoperable, artificial

pancreas system.

JDRF has been a leader in the

development of artificial pancreas systems

since starting the Artificial Pancreas

Project 15 years ago helping to accelerate

the development of transformative

therapies that make life better for people

living with T1D.

www.jdrf.org

T:SLIM FOR

CHILDREN

New ABCD audit data demonstrate

better glucose control and fewer hospital

admissions for people with Type 1 diabetes

using the Flash glucose monitoring system

(Abbott's FreeStyle Libre).

According to Dr Chris Walton, "People

in the UK living with Type 1 diabetes who

use the FreeStyle Libre system spend a

greater time in the ideal glucose range

over a 14-day period the more they

scan and this increased time in range is

associated with a significant improvement

in HbA1c. People with Type 1 diabetes

who used the FreeStyle Libre showed a

reduction in diabetes distress and were

less likely to be admitted to hospital."

This is according to new audit data

released at The American Diabetes

Association (ADA) 80th Scientific Sessions

AUDIT ON ABBOTT UVA's Department of Ophthalmology and

Department of Biomedical Engineering,

said. "The benefit that they obtained is

saturated at low levels of exercise."

The scientists aren't certain exactly

how exercise is preventing the blood

vessel overgrowth. There could be a

variety of factors at play, they say, including

increased blood flow to the eyes

Gelfand noted that, with humans, the

onset of vision loss is often associated

with a decrease in exercise. "It is fairly well

known that as people's eyes and vision

deteriorate, their tendency to engage in

physical activity also goes down," he said.

"It can be a challenging thing to study in

older people. How much of that is one

causing the other?"

"The next step is to look at how and

why this happens, and to see if we can

develop a pill or method that will give you

the benefits of exercise without having to

exercise," Gelfand said.

To read the study click HERE.

in June 2020 by the Association of British

Clinical Diabetologists (ABCD). The ABCD

audit, an independent national audit

supported by an unrestricted educational

grant from Abbott, looks at the real-world

experience of people using the FreeStyle

Libre system and how it impacts their

glycaemic control. Clinicians are invited

to submit the data they collect to a secure

web-based tool. A total of114 NHS sites

have registered for the audit.

www.abcd.care

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