Professor John Pickup diabetes insulin pump research

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that patients would not like or tolerate

wearing a machine like this. All turned

out not true in reality. It's interesting to

note the early correlation that insulin

pump users were among the very first

people to take up home blood testing

too, gaining the greater control that leads

to far fewer hypos. People with diabetes

who understood about the benefits of

improved control did not worry overly

about either wearing a pump or pricking

their fingers."

The first full research paper on CSII by

J Pickup et al was published in the BMJ

in 1978.

A company based in south Norwood

called Muirhead Ltd, which manufactured

new-fangled fax machines, made the early

pumps. In 1983 they had made the first

microprocessor-controlled insulin pump,

later licensed to Novo Nordisk. The first

insulin used in pumps was pork Actrapid,

but by the late 1980s genetic engineering

of human insulin using bacteria had

been done, leading to the first time any

human had been given a synthesised

protein. Guys Hospital helped to test the

safety and efficacy of this innovation in

medical care. Pickup recalls, "Everyone

was terrified of what might happen." And

the brave souls who tested it? Step up

candidate number one, Professor Harry

Keen. And candidate number two? Dr

John Pickup.

It was around this time, 1983, that the

team at Guys started to research glucose

sensors, part of the direction of travel to

today's CGM options, which are now

becoming much more widely used and

accepted, though more than 30 years later.

Are we there yet?

We've come a long way, people, but it's

been slow progress. Bearing in mind the

fact that this technology has been around

a while, how come we have seen what is

arguably a very low uptake of it? Pickup

says that there is "clear effectiveness of

the use of this technology, but availability

is highly variable. New technology can be

more expensive than existing technology,

and undoubtedly there is also still some

resistance to it both from patients and

HCPs. However, what has been proven

with insulin pump use is that severe

hypos are reduced, by up to 75%, with an

almost immediate 0.6% improvement in

HbA1c after switching from multiple daily

injections."

Speaking with Pickup, it's easy to see

that he's just as frustrated as anyone else

at the slow progress in terms of uptake

and availability, with wearable diabetes

technology still being used by relatively

continued over

John Pickup, left, with Keen

in the early 1970s holding

one of the earliest ever

insulin pumps.

Index

  1. Desang diabetes magazine diabetes information
  2. Medtronic Minimed 640G insulin pump
  3. Desang diabetes magazine diabetes information, Sue Marshall
  4. Desang diabetes magazine diabetes news
  5. Desang diabetes magazine diabetes news
  6. Desang diabetes magazine diabetes news
  7. Dexcom CGM, continuous glucose monitoring
  8. Desang diabetes magazine diabetes news, diabetes charities
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  10. Page 0010
  11. Abbott Freestyle Libre blood glucose sensor
  12. Freestyle Libre blood glucose sensor
  13. Diabetes UK helpline
  14. Desang diabetes magazine diabetes diet
  15. Desang diabetes magazine diabetes diet
  16. Diabetes management equipment, Frio sharps bin
  17. Page 0017
  18. Accu-Chek Mobile blood glucose system
  19. Accu-Chek Mobile blood glucose system
  20. Professor John Pickup diabetes research, insulin pump research
  21. Professor John Pickup diabetes insulin pump research
  22. Professor John Pickup diabetes insulin pump research
  23. Omnipod Insulet insulin pump with insulin pods
  24. Professor John Pickup diabetes insulin pump research
  25. Ascensia Contour Next One Diabetes blood test meters
  26. Professor John Pickup diabetes insulin pump research
  27. Professor John Pickup diabetes insulin pump research
  28. Language matters in diabetes care
  29. Language matters in diabetes care
  30. Making Carbs Count cherries
  31. Jerte Picota cherries, Making Carbs Count
  32. Accu-Chek Insight insulin pump
  33. Accu-Chek Insight insulin pump
  34. Free diabetes magazine from Desang Diabetes Media

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