Professor John Pickup diabetes insulin pump research

LIVINGLIVING

since saving the lives of millions. However

it wasn't until the mid-'60s to '80s that

there were more significant breakthroughs

in the treatment of T1D with home-blood

testing, insulin pens, and pumps coming

along. But where did they come along

from?

Portable option

Pickup was part of the world's first trial of

a portable insulin pump. He looks back,

"It was already becoming apparent that

good control was directly related to a

reduction in the development of diabetes

complications, before we even had the

results of the DCCT* trial that proved this

as a fact. Prior to that we did not know for

certain that sustained high blood sugars,

or overall extreme glucose variation was

what was actually causing the damage."

In 1974 Pickup had met Dr John

Parsons, a pharmacologist at the National continued over

Institute for Medical Research in Mill Hill,

London. He had a basic drugs infuser -

called the Mill Hill Infuser - which was at

that time used for infusing parathyroid

hormone into animals. They actually met

in Boston, Massachusetts, Pickup at that

point being in the Massachusetts General

Hospital Endocrine Unit while Parsons

was a senior medical researcher on leave

from Mill Hill at the Mass General, which

was a well-known centre of calcium

metabolism at the time, Parsons being

interested in parathyroid hormone action.

"I think we bonded because he knew

my PhD supervisor at Oxford, and it was

he who recommended I meet up with

Parsons when later I went to Boston as

a clinical medical student," recalls Pickup.

"We then wondered if the Mill Hill Infuser

could be used for delivering insulin, and

in that way mimic the control of someone

who did not have diabetes," he says,

"We knew it would need to include

patient-activated boosts (or boluses) at

mealtimes."

An infuser - or pump -- was then made

for human use, a pump which now resides

in the Science Museum in London. "From

this point on," says Pickup, "dramatic

improvement in diabetes control was

probably possible."

A little while after, Pickup and Keen

presented the concept at the European

Association for the Study of Diabetes

(EASD) held in Geneva in 1977. Pickup

recalls, "Feedback was generally very

positive and people were intrigued,

though there were many reservations

and doubts about whether the technique

had any future in diabetes care. There

was a worry that continuous infusion

would lead to much hypoglycaemia and

Index

  1. Desang diabetes magazine diabetes information
  2. Medtronic Minimed 640G insulin pump
  3. Desang diabetes magazine diabetes information, Sue Marshall
  4. Desang diabetes magazine diabetes news
  5. Desang diabetes magazine diabetes news
  6. Desang diabetes magazine diabetes news
  7. Dexcom CGM, continuous glucose monitoring
  8. Desang diabetes magazine diabetes news, diabetes charities
  9. Desang diabetes magazine diabetes news
  10. Page 0010
  11. Abbott Freestyle Libre blood glucose sensor
  12. Freestyle Libre blood glucose sensor
  13. Diabetes UK helpline
  14. Desang diabetes magazine diabetes diet
  15. Desang diabetes magazine diabetes diet
  16. Diabetes management equipment, Frio sharps bin
  17. Page 0017
  18. Accu-Chek Mobile blood glucose system
  19. Accu-Chek Mobile blood glucose system
  20. Professor John Pickup diabetes research, insulin pump research
  21. Professor John Pickup diabetes insulin pump research
  22. Professor John Pickup diabetes insulin pump research
  23. Omnipod Insulet insulin pump with insulin pods
  24. Professor John Pickup diabetes insulin pump research
  25. Ascensia Contour Next One Diabetes blood test meters
  26. Professor John Pickup diabetes insulin pump research
  27. Professor John Pickup diabetes insulin pump research
  28. Language matters in diabetes care
  29. Language matters in diabetes care
  30. Making Carbs Count cherries
  31. Jerte Picota cherries, Making Carbs Count
  32. Accu-Chek Insight insulin pump
  33. Accu-Chek Insight insulin pump
  34. Free diabetes magazine from Desang Diabetes Media

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