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LIVINGLIVING

In our next issue there will be a

specific update on the BiAP pump being

investigated by the Diabetes Technology

Research Group (Imperial College London

at St Mary's Hospital) using a 'bio-inspired'

approach - mimicking the physiology of

the human body, as well as an overview

of current - and coming - CGM systems.

Four separate projects have been funded

by the National Institute of Diabetes

and Digestive and Kidney Diseases

(NIDDK), which are designed to be the

potential last steps between testing the

fully automated devices and requesting

regulatory approval for permanent use.

A successful artificial pancreas would be

a life-changing advance for many people

with Type 1 diabetes. NIDDK is part of

the National Institutes of Health in the US.

Dr. Guillermo Arreaza-Rubín, director of

NIDDK's Diabetes Technology Program,

says, "These studies aim to collect the

data necessary to bring artificial pancreas

technology to the people who need it.

Results from these studies could change

and save lives."

These studies will look at factors

including safety, efficacy, user-friendliness,

physical and emotional health of

participants, and cost. The Jaeb Center

for Health Research in Tampa, Florida, will

serve as coordinating centre.

1. The International Diabetes ClosedLoop trial, led by Drs. Boris Kovatchev

and Stacey Anderson (both University

of Virginia), will test an automated insulin

delivery system called inControl. The

trial, which uses smartphones, will follow

240 people age 14 and up with Type 1

diabetes for six months at several sites

in the US and Europe. A second, sixmonth

study will recruit from the 180

US participants of the first trial to test an

alternative algorithm.

2. Recruitment is beginning for people

aged 6-18 for a full-year trial of an artificial

pancreas led by Dr. Roman Hovorka

(University of Cambridge). The study

seeks to enroll 130 young people to use

of an artificial pancreas system that uses

Diabetes and technology:

artificial pancreas studies around the world

a smartphone as one component. The

study will be conducted at sites in the US

and the UK.

3. Starting in late 2017, research led

by Drs. Richard Bergenstal (International

Diabetes Center, Minneapolis), and

Moshe Phillip (Schneider Children's

Medical Center, Israel), will compare

the FDA-approved hybrid artificial

pancreas to a next-generation system,

programmed to further improve glucose

control, particularly around mealtime.

One hundred young people will test each

system for three months at sites in the US

and in Germany, Israel and Slovenia.

4. In mid-2018, another 'bionic

pancreas' study will be led by Drs. Steven

Russell (Massachusetts General Hospital

in Boston), and Ed Damiano (Boston

University) will enroll 312 people ages

18 and older. The six-month study uses

a bihormonal "bionic pancreas" system,

with a dual-chamber pump to deliver both

insulin and its counteracting hormone,

glucagon, using tested algorithms for

automated dual-hormone delivery. The

study will take place at sites in the US.

available they will all have apps that mean

that you will easily be able to see what's

going on with your diabetes control by

looking at the app on your smartphone,

so you won't be out of the loop entirely.

And for what it's worth, I personally

believe that nothing beats a blood test if

you want to really know what's going on.

While the human factor will always be

involved - they will after all be strapped

onto humans - medical advice from

those working on these research trials is

to 'let the machine do the work'. It seems

that things go wrong when the diabetics

on the trials take matters into their own

hands and intervene. It seems that, as

with most new technology, it will take us

a while to learn to trust it, which sounds

sensible to me.

One of the downsides will be access

- how long will it take before artificial

pancreas pumps are really widely

available? Although there is a lot of

research under way, it seems like we're a

few years away from there being a good

choice available. The only one looking to

be available this year in the UK is the MiniMed 670G from

Medtronic although there

is no date set for that yet.

Index

  1. Page 0001
  2. Abbott Freestyle Libre, Flash Glucose Monitoring, blood testing without lancets
  3. Sue Marshall, The Grumpy Pumper, Desang Diabetes Magazine, hypos, DRWF, Diabetes UK, CGM, the full s
  4. DRWF, diabetes news, Adocia insulin, Type 2 diabetes
  5. Sanofi diabetes care, diabetes highs and lows
  6. Page 0006
  7. Diabetes Risk Score, Professor Khunti, Leicester Diabetes Centre
  8. diabetes kit
  9. Medtronic diabetes insulin pump, Medtronic Minimed 640G, and Medtronic Enlite CGM,
  10. Desang diabetes magazine diabetes diet
  11. diabetic diet, carbs and cals, Chris Cheyette and Yello Baliola
  12. Page 0012
  13. National Institute of Medical Herbalists
  14. my diabetes kit, the grumpy pumper
  15. my diabetes kit, the grumpy pumper
  16. my diabetes kit, the grumpy pumper, insulin pump, Animas Vibe, Dexcom
  17. Ascensia Contour Diabetes blood test meters
  18. my diabetes kit, the grumpy pumper, insulin pump, Animas Vibe, Dexcom
  19. Page 0019
  20. Page 0020
  21. Page 0021
  22. Sue Marshall, closed loop insulin pump, artificial pancreas, CGM
  23. artificial insulin pump, bionic bi-hormonal pump
  24. artificial insulin pump, Medtronic 640g insulin pump
  25. Bionic pancreas Edward Damiano, Steven Russell, Firas El-Khatib, Boston University
  26. Agamatrix Wavesense Jazz Wireless, blood test meter and app
  27. artificial insulin pump, bionic pancreas, CGM, type 1 diabetes, Type 2 diabetes
  28. Page 0028
  29. Medtronic diabetes insulin pump, Medtronic Minimed 640G, and Medtronic Enlite CGM,
  30. Chris Chapman GlucoRx, type 2 diabetes, blood test meters
  31. Chris Chapman GlucoRx,
  32. Making Carbs Count pseudograins
  33. Making Carbs Count pseudograins
  34. Accu-Chek Insight insulin pump
  35. Page 0035
  36. Page 0036

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