diabetes news, diabetes research news, diabetes information, diabetes news

5

NEWS

IMMUNOTHERAPY

DELAYS T1

A landmark trial shows that an immunotherapy drug

can delay Type 1 diabetes by an average of three years.

Previously, in 2019, researchers from the TrialNet group

found that Teplizumaub could delay a diagnosis of Type 1

diabetes by two years in people at high risk of developing

the condition. Now the researchers have revealed their

latest results. They checked on the participants six

years after their initial treatment and found that the

drug continues to have a positive effect. Those given

Teplizumab were less likely to be diagnosed with Type 1

diabetes than a comparison group given a placebo.

The new results show that 78% of people at high risk

of developing Type 1 diabetes in the placebo group were

diagnosed with the condition during the trial, compared

to 50% of those treated with the drug. The study

identified a higher risk of diabetes through a blood test

that looks at genetics and specific antibodies in the blood.

The average time for people in the placebo group to

develop Type 1 diabetes was two years, while the average

time in those taking Teplizumab was five years.

DIABETES TECH

GAINS MOMENTUM

STEM CELL RESEARCH FOR TYPE 1

The US FDA has granted Fast

Track Designation for VX-880, an

investigational allogeneic human

stem cell-derived islet cell therapy

for people with Type 1 diabetes.

The therapy, VX-880 (formerly

known as STx-02), is being evaluated

for patients who have T1D with

impaired hypoglycaemic awareness

and severe hypoglycaemia in a clinical

trial by Vertex Pharmaceuticals

Incorporated. VX-880 could restore

the body's ability to regulate glucose

levels by restoring pancreatic islet

cell function, including insulin

production. The trial will involve

an infusion of fully differentiated,

functional islet cells and the chronic

administration of concomitant

immunosuppressive therapy to

protect the islet cells from immune

rejection.

"It's a remarkable time for

Type 1 diabetes research efforts

worldwide, as this investigational

treatment enters the clinic," said

Camillo Ricordi, M.D., Professor of

Surgery, Director of the Diabetes

Research Institute (DRI) and the Cell

Transplant Center at the University

of Miami Miller School of Medicine,

and Steering Committee Chair for

the VX-880 clinical trial. The field's

experience with the limited cadaveric

islet transplants available, where

some patients have experienced

prolonged insulin independence for

years, provides important proofof-concept

for the potential of cell

therapy to be transformative for

patients living with Type 1 diabetes."

More people with diabetes are moving towards

wearables and virtual care, accelerated by the

coronavirus pandemic, a survey conducted in the US has

found. Pump makers Insulet and Tandem have reported

solid results for 2020, and both companies expect that

momentum to continue, while Medtronic has a renewed

focus on diabetes tech.

The survey, by SVB Leerink, reported that adoption

among patients with Type 1 diabetes is projected to

grow from 51% in 2021 to 62% in 2024. SVB Leerink

commissioned MEDACorp to survey 101 endocrinologists

and nurse practitioners, representing 124,847 diabetes

patients. The group is a global network of healthcare

professionals and part of SVB Leerink. Adoption among

insulin-intensive Type 2 patients is projected to grow

from 17% in 2021 to 23% in 2024.

To read more CLICK HERE.

INFLAMMATORY LINK

A review suggests that adverse consequences

currently attributed to obesity could be attributed

to hyperinsulinemia - a condition where the amount

of insulin in the blood is higher than normal among

people without diabetes. In the systematic review and

meta-analysis of 5,603 participants from 60 studies, the

association between period 1 (preceding) levels of fasting

insulin and period 2 (subsequent) BMI was positive and

significant. To read more CLICK HERE.

Index

  1. Desang Diabetes Magazine, free diabetes magazine
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  8. Abbott Freestyle Libre 2, Flash Glucose Monitoring, FSL2, Abbott Wellness Factory
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  10. JDRF UK Type 1 diabetes charity
  11. Medtrum A6 Touchcare patch pump and CGM in harmony
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  13. Air Liquide Healthcare UK, Tandem t:slim insulin pump, , Control-iQ
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  20. Medtronic MiniMed 780G System Automated for an easier way to stabilise glucose levels.
  21. Medtronic MiniMed 780G System Automated for an easier way to stabilise glucose levels.
  22. Medtronic MiniMed 780G System Automated for an easier way to stabilise glucose levels.
  23. Spirit Pharmacy for people with diabetes
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  25. Medtronic Guardian Connect CGM sensor for diabetes
  26. Medtronic MiniMed 780G System Automated for an easier way to stabilise glucose levels.
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  28. Desang Magazine, My Diabetes Kit, Charlotte Mitchell the guilty diabetic
  29. Desang Magazine, My Diabetes Kit, Charlotte Mitchell the guilty diabetic
  30. Desang Magazine, My Diabetes Kit, Charlotte Mitchell the guilty diabetic
  31. Diabetes technology education from Diabetes Technology Network DTN
  32. Desang Magazine, My Diabetes Kit, Charlotte Mitchell the guilty diabetic
  33. insulin pump, Dana RS system, artificial pancreas, Advanced Therapeutics UK, CamAPS FX, Dexcom G6
  34. Sue Marshall, Desang Diabetes Magazine, diabetes technology
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  38. Free Desang Diabetes Magazine, diabetes technology
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  40. desang, diabetes diet, diabetic diet, counting carbohydrates, food for diabetes
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  45. Desang diabetes kitbags, Desang diabetes diaries
  46. Free Desang Diabetes Magazine, diabetes technology

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