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Research has shown that losing just two

to three kilograms (KGs) of weight and

exercising for two years almost halves the

risk of developing Type 2 diabetes.

The Norfolk Diabetes Prevention Study

(NDPS) findings - the largest diabetes

prevention research study in the world

in the last 30 years - involved more than

1,000 people with pre-diabetes between

2011 and 2018. The research team found

that support to make modest lifestyle

changes, including losing two to three

KGs of weight and increased physical

activity over two years, reduced the risk

of Type 2 diabetes by 40 to 47 per cent.

The trial tested a simple lifestyle

intervention, which helped people make

small achievable lifestyle changes that led

to a modest weight loss, and increases

in physical activity. Importantly, these

changes were sustained for at least

two years, and the weight loss was not

regained. These findings are significant

as they show that a 'real-world' lifestyle

programme really can make a difference in

helping people reduce their risk of Type 2.

Professor Mike Sampson, NDPS Chief

Investigator and Consultant in Diabetes at

Norfolk and Norwich University Hospital

(NNUH), said: "We are delighted with

the results of this trial, as until now no

one was very sure if a real-world lifestyle

programme prevented Type 2 diabetes in

the pre-diabetes population we studied,

as there have been no clinical trials that

had shown this.

"We have now shown a significant

effect in Type 2 diabetes prevention, and

we can be very optimistic that even a

modest weight loss, and an increase in

physical activity, in real-world programmes

like this have a big effect on the risk of

getting Type 2 diabetes."

The results are published in the JAMA

Internal Medicine journal.

The Type 1 diabetes charity JDRF has

hailed its Ambassador Nina Wadia (right),

who has received an OBE in the New

Year's Honours List for her services to

charity and entertainment. The actress is

well-known for her roles in EastEnders,

Still Open All Hours and Goodness

Gracious Me. She has supported JDRF

since her son, Aidan, was diagnosed with

the condition at the age of 10. Michael

Connellan, Head of External Affairs at

JDRF, said: "Nina Wadia has been a true

leader in the Type 1 diabetes community

following her son's diagnosis. We are

delighted that she has been recognised in

the New Year's Honours. Congratulations,

Nina." Diabetes professor Partha Kar has

been awarded an OBE for services to

people with diabetes in the New Year's

Honours list. Kar has been a Consultant in

Diabetes & Endocrinology at Portsmouth

Hospitals NHS Trust since 2008. He was

the Clinical Director of Diabetes from 2009

to 2015 and is the Super Six Diabetes

Model pioneer, which aims to deliver

diabetes care differently, recognised

as a good example of integrated care.

He is also a Professor at the University

of Leicester working with the Leicester

Diabetes Centre. In addition, Andrew

Hattersley, Professor at the University

of Exeter and diabetes consultant at the

Royal Devon & Exeter NHS Foundation

Trust, has won the Belgian Baillet Latour

Health Prize 2020.

NEW T2 DRUG

The Low Carb Program app is to become

accessible using a personalised NHS

login.

The program provides structured

education and long-term behaviour

change support through health coaching,

and personalised user experience to

support patients to achieve self-selected

health goals by reducing the amount of

carbohydrates to 130 grams a day. The

app is used by people with obesity, prediabetes,

Type 2 diabetes, non-alcoholic

fatty liver disease and polycystic ovarian

syndrome.

NHS login is a single, secure login that

allows users quick access to health and

social care apps and websites wherever

you see the NHS login button. This is

already available via the web platform and

will be made available to iOS and Android

users in early 2021.

www.lowcarbprogram.com

A medication to treat Type 2 diabetes

has significantly reduced blood sugar

and body weight in participants of a latephase clinical trial.

Eli Lilly's Tirzepatide is in phase

3 development for blood glucose

management in adults with Type 2 diabetes

and for chronic weight management. It is

a once-weekly dual glucose-dependent

insulinotropic polypeptide (GIP) and

glucagon-like peptide-1 (GLP-1) receptor

agonist that integrates the actions of both

incretins into a single novel molecule. GIP

is a hormone that may complement the

effects of GLP-1 receptor agonists. In

preclinical models, GIP has been shown

to decrease food intake and increase

energy expenditure, therefore, resulting in

weight reductions, and when combined

with a GLP-1 receptor agonist, may result

in greater effects on glucose and body

weight. www.lilly.com

NHS LOGIN

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  11. Air Liquide Healthcare UK Tandem t:slim insulin pump with Control IQ
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  14. Abbott Freestyle Libre, Flash Glucose Monitoring
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  16. Diabetes kit reports, closed loop insulin delivery
  17. Ascensia Contour Next One Diabetes blood test meters
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  19. Insulet Omnipod DASH insulin pump with insulin pods, podders, Omnipod DASH Personal Diabetes Manager
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  33. Roche Diabetes Care
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  35. Dexcom G6 CGM, continuous glucose monitoring
  36. Making Carbs Count, Carbohydrate counting for diabetes
  37. Making Carbs Count, Carbohydrate counting for diabetes
  38. Making Carbs Count, Carbohydrate counting for diabetes
  39. Page 0039
  40. Page 0040

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