Diabetes kit reports, closed loop insulin delivery

KIT

KIT

REPORT

The tale of Lilly, Ypsomed and the development of an automated

insulin delivery (AID) system. We're a long way from the H-Tron now!

Eli Lilly, one of the Big

Three insulin makers

that's had its eyes on

diabetes technology for

several years, is making

moves to launch a new insulin pump and

automated insulin delivery (AID) system in

the United States.

This is not the proprietary pump that

Lilly's diabetes division had been codeveloping for several years alongside its

connected insulin pen. Rather, Lilly has

scrapped that project and announced a

new collaboration with Switzerland-based

Ypsomed, which already markets a unique,

ultra-thin icon-driven insulin pump outside

the US. The deal grants Lilly exclusive

rights to commercialize the YpsoPump

in the U.S. once the latest model is

submitted and approved by the Food and

Drug Administration (FDA). It also sets the

stage for a future smartphone-based AID

system combining the YpsoPump with

the Dexcom CGM (continuous glucose

monitor) via a controlling algorithm that

automates insulin dosing.

"This is the first in-depth technical

cooperation between an insulin pump

manufacturer and a pure insulin company,"

said Thomas Kutt, head of investor

relations for Ypsomed Holdings AG in

Switzerland. "There is a lot of potential to

improve and advance technology that is

sustainable for people with diabetes."

Back in the 1980s, Ypsomed

developed and launched the Diesetronic

H-Tron - one of the first insulin pumps

ever available - alongside the initial

Minimed pump that was later acquired by

Medtronic. Diesetronic was discontinued

in 2003 after it was sold to Roche, and

that insulin pump evolved into the AccuChek Spirit

pump. Ypsomed launched its

own mylife YpsoPump in 2016. That is

now available in more than 20 countries

outside the U.S.

Compact solution

YpsoPump uses traditional tubing but

is compact and flexible to use. About

the size of a standard business card, it

weighs 83g (including a full reservoir and

batteries). It uses a 1.6 mL (160 units)

glass cartridge insulin reservoir that can

accommodate either a self-filled cartridge

with any leading insulin brand or a prefilled

cartridge of NovoRapid.

Based on the Dexcom integration

announced in May 2020, Ypsomed plans

to tie CGM data into the mylife mobile app

(called mylife Assist) for quick-glance info

and decision-making. This is planned for

the first half of 2021, outside the US. With

CGM data already on board, Ypsomed

plans to launch a bolus calculator function

and remote bolusing from the smartphone

app in late 2021, called mylife Dose. To

date, FDA regulators have not yet allowed

this functionality on any devices in the US.

YpsoLoop would be an additional

closed loop functionality offered by

Ypsomed, separate from what is now in

development with Lilly. The company tells

us they have not yet decided on which

smart algorithm might be used, but they

have many options to consider, including

Dexcom's own TypeZero algorithm. While

both Assist and Dose are planned for

2021, the YpsoLoop system isn't planned

until mid-2023 at the earliest.

Single solution

Ypsomed has confirmed that part of its

agreement with Lilly for US distribution

is to offer the new system compatible

with Lilly-branded insulins only with

no plans to offer compatibility with

other insulin products in the future. Lilly

communications manager Maggie Pfeiffer

said they're working with Ypsomed to

develop 1.6 mL cartridges for Lilly's rapidacting

insulins that will be compatible with

the new YpsoPump-based AID system.

Written by Mike Hoskins for Healthline

An Ypsomed Ypsopump in a man's hands.

www.healthline.com

COMING TO OUR AID

Index

  1. Free online Desang diabetes magazine diabetes information
  2. Medtrum A6 Touchcare patch pump and CGM in harmony
  3. Desang diabetes, magazine diabetes information, Sue Marshall diabetes
  4. Desang diabetes magazine, diabetes news
  5. Diabetes kit, diabetes magazine diabetes information
  6. Diabetes kit, diabetes magazine diabetes information
  7. Desang diabetes magazine, diabetes news
  8. Desang diabetes magazine, diabetes news
  9. Desang diabetes magazine, diabetes news, Glooko Diasend Academy
  10. Glooko Diasend Academy
  11. Air Liquide Healthcare UK Tandem t:slim insulin pump with Control IQ
  12. diabetes insulin pumps
  13. Page 0013
  14. Abbott Freestyle Libre, Flash Glucose Monitoring
  15. Abbott Freestyle Libre, Flash Glucose Monitoring
  16. Diabetes kit reports, closed loop insulin delivery
  17. Ascensia Contour Next One Diabetes blood test meters
  18. Diabetes kit reports, closed loop insulin delivery
  19. Insulet Omnipod DASH insulin pump with insulin pods, podders, Omnipod DASH Personal Diabetes Manager
  20. Diabetes kit reports, closed loop insulin delivery
  21. BD, Becton Dickinson, injection technique, BD pen needles, BD and Me
  22. Desang diabetes magazine, diabetes diet
  23. Medtronic Guardian Connect CGM sensor for diabetes
  24. Cities Changing Diabetes, Novo Nordisk diabetes
  25. Cities Changing Diabetes, Novo Nordisk diabetes
  26. Cities Changing Diabetes, Novo Nordisk diabetes
  27. Cities Changing Diabetes, Novo Nordisk diabetes
  28. Cities Changing Diabetes, Novo Nordisk diabetes
  29. insulin pump, Dana RS system, artificial pancreas, Advanced Therapeutics UK, CamAPS FX, Dexcom G6
  30. Desang Diabetes Magazine, free diabetes magazine, living with diabetes
  31. Desang Diabetes Magazine, free diabetes magazine, living with diabetes
  32. Desang diabetes, Inside diabetes guides, guide to injecting insulin, guide to injecting for people w
  33. Roche Diabetes Care
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  35. Dexcom G6 CGM, continuous glucose monitoring
  36. Making Carbs Count, Carbohydrate counting for diabetes
  37. Making Carbs Count, Carbohydrate counting for diabetes
  38. Making Carbs Count, Carbohydrate counting for diabetes
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