diabetes news, diabetes research news, diabetes information, diabetes kit, diabetes technology

4

NEWS

Veri good

idea?

A food intelligence company has

raised $4 million in funding to start

shipping its linked Freestyle Libre to

the US to help people monitor their

blood glucose for preventative health.

Lower-carb option for T2

A lower carbohydrate diet is an effective short-term option for adults

living with Type 2 diabetes and overweight or obesity, concludes a report

by the Scientific Advisory Committee on Nutrition (SACN). The report,

co-chaired with Diabetes UK, is based on a robust assessment of existing

evidence around weight change, blood glucose management, blood fats

and medication use. It suggests that a diet lower in carbohydrates is an

effective option for up to six months for adults living with Type 2 diabetes

and overweight or obesity.

People on lower carbohydrate diets lost more weight than those on

higher carbohydrate diets in the first three months but not after, so it's

unclear if the benefits of a lower carbohydrate diet are due to this early

weight loss. Overall, the quality of the evidence wasn't strong enough to

recommend a lower carbohydrate diet for longer than six months.

Douglas Twenefour, co-chair of the joint working group and Deputy

Head of Care of Diabetes UK, said: "We know that for most people

with type 2 diabetes, managing their weight is key to managing their

condition. Health professionals should support any evidence-based

dietary approach that helps achieve long-term weight reduction, and

this can include a lower carbohydrate diet. It is vital that people get

the support of their healthcare team, so that any impact on diabetes

management or medications can be closely monitored."

To read the report, CLICK HERE.

T1's cellular culprit

Researchers at the University of California San Diego School of Medicine

have identified a predictive causal role for specific cell types in Type

1 diabetes by mapping its genetic underpinnings. The mechanisms of

Type 1 diabetes are poorly understood. Because it has a strong genetic

component, numerous genome-wide association studies (GWAS) have

been conducted. Researchers compare whole genomes of people with the

same condition, searching for differences in the genetic code that may be

associated with it.

In Type 1 diabetes, identified at-risk variants have primarily been

found in the non-coding regions of the genome. The researchers

integrated GWAS data with epigenomic maps of cell types in peripheral

blood and the pancreas. Epigenomic mapping details how and when

genes are turned on and off in cells, determining the production of

proteins vital to specific cellular functions. The study analysed 520,580

genome samples to identify 69 novel association signals. They then

mapped 448,142 cis-regulatory elements (non-coding DNA sequences in

or near a gene) in pancreas and peripheral blood cell types.

Senior author Kyle Gaulton, PhD, commented, "By combining these

two methodologies, we were able to identify cell type-specific functions

of disease variants and discover a predictive causal role for pancreatic

exocrine cells in type 1 diabetes, which we were able to validate

experimentally." Co-author Maike Sander, MD, said the findings represent

a significant leap in understanding the causes of type 1 diabetes. The

findings are published in the May 2021 issue of Nature.

Based in Helsinki, Finland,

Veri uses the Libre CGM with it's

own accompanying app to help

people understand their optimal

diet to improve metabolic health.

The idea is to make blood glucose

readings as commonplace as heart

readings, which are easily tracked

by smartphones and wearable tech.

Veri's app, alongside the CGM,

provides real-time feedback on food

choices, analysing personalised blood

glucose levels alongside exercise and

sleep habits.

Available in the US this June, a

single sensor costs $129, or two for

$199. One sensor lasts two weeks.

Users can also subscribe every

month. For a single sensor, the

subscription fee is €89 ($108 US) per

month.

www.veristable.com

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