Desang diabetes magazine diabetes news, Type 1 diabetes, Type 2 diabetes

NEWS

CLINICAL COLLABORATIVE

and both disorders associated with

metabolic changes including amplified

inflammatory responses in adipose

tissue, this discovery could help in the

understanding and treatment of these

conditions. In an experimental model, it

was determined that the number of Tregs

in adipose tissue increases in response

to different environmental stimuli. These

stimuli included a short-term cold

treatment, stimulation of the sympathetic

nervous system and short-term highcaloric exposure

(see image).

The Association of British Clinical

Diabetologists has announced the

launch of the Type 1 Diabetes Clinical

Collaborative in the UK. This is a

collaborative of healthcare professionals

working in multi-disciplinary teams

providing care for adults with Type 1

diabetes across the UK. The committee

is made up of individual healthcare

professionals from all the disciplines from

the four nations who are passionate about

raising the standards of care for people

with Type 1 diabetes. It is currently chaired

by Dr Rob Gregory, immediate past chair

of ABCD, with Professor Stephanie Amiel

and Professor Simon Heller as nonexecutive

co-chairs. Diabetes UK is a

partner in this initiative.

The Mission Statement of the

collaborative is, "To ensure that everyone

with Type 1 diabetes has access to a

suitably-trained multidisciplinary specialist

team for expert assessment, care and

support for self-management."

The local Lincolnshire diabetes group has joined forces with four Clinical Commissioning

Groups (CCGs) to launch an innovative project in the area which aims to transform the

lives of people living with Type 2 diabetes. Over the next two years the project is set to

reach more than 16,000 people living with the condition via eight 'Living with Diabetes

Days', as well as thousands of information packs and new peer support groups. A Living

with Diabetes Day is taking place in Gainsborough on 18 October from 10:00. The event

is free and aims to show people how to better manage their diabetes day-to-day. There

will be diabetes experts available to answer questions and there will be a chance to meet

other people diagnosed with Type 2 diabetes. On 15 November another Living with

Diabetes Day is taking place in Spalding.

For more information call 01922 614500, email midlands@diabetes.org.uk

lincolnshire.diabetesukgroup.org

The 24-week results from a trial, DEPICT-1, people with Type 1 diabetes taking the oral

selective SGLT-2 inhibitor class of diabetes medicines show that dapagliflozin, as an

adjunct to insulin, provides significant and clinically relevant benefits in terms of glycaemic

control and weight reduction, together with a reduction in insulin dose, and is not

associated with an increase in the occurrence of hypoglycaemia or diabetic ketoacidosis.

To read more about SGLT-2 inhibitors CLICK HERE.

LINKS TO LINCS

DEPICT-1 RESULTS

"A better understanding of the

immunological mechanisms involved

in the target tissue will be critical for the

development of personalized interventions

in order to improve adipose tissue function

during obesity and diabetes", said the

leader of the study, Carolin Daniel. "Our

experiments show for the first time that

Tregs can support fat depots in dealing

with environmental challenges."

Prof. Dr. Matthias Tschöp, also

involved in the study, added, "Our

findings highlight the complex interactions

between our body and the environment.

We have known for a while that

hormones play a key role here - but

now have to accept that immune cells

may be just as important for a balanced

metabolism. These insights therefore help

us tremendously with designing more

efficient ways to therapeutically optimize

when and how to store calories."

Regulatory T-cells suppress unwanted

immune reactions and thereby prevent

autoimmune diseases. Brown adipose

tissue is found in almost all mammals,

including humans. Its cells produce heat

by oxidizing sugars and fatty acids. This

makes them an interesting target for

pharmacological treatment of obesity.

For the latest news on Continuous

Glucose Monitoring and Flash Glucose

Monitoring (they are different), see our

feature A SENSOR ADVENTURE, p.20.

Index

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  3. Desang diabetes magazine diabetes information, Sue Marshall
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  12. diabetic diet
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  14. Tim Omer, hypodiabetic, nightscout, CGM hackers, CGM sensors
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  17. Tim Omer, hypodiabetic, nightscout, CGM hackers, CGM sensors
  18. London Medical, London Diabetes Centre, private diabetes clinic
  19. London Medical, London Diabetes Centre, private diabetes clinic
  20. CGM sensors, continuous glucose monitor, Dexcom, Medtronic Enlite, Eversense implantable CGM, Abbott
  21. CGM sensors, continuous glucose monitor, Dexcom, Medtronic Enlite, Eversense implantable CGM, Abbott
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  26. Neuropad diabetes footcare
  27. diabetic diet, Dr Malhotra, the pioppii diet
  28. Making Carbs Count goat meat
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  30. DRWF diabetes research and wellness foundation events
  31. Abbott Freestyle Libre, Flash Glucose Monitoring, blood testing without lancets
  32. Making Carbs Count, goat meat curry, Romy Gil
  33. Accu-Chek Insight insulin pump
  34. Desang Diabetes Magazine, Living with diabetes, the diabetic diet, carb counting

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