Diabetes news, Metformin, FreeStyle LIbre, IDDT



Win a FreeStyle Libre Flash Glucose

Monitoring System. As they say, the days

of routine glucose testing with lancets,

test strips and blood are over. To be in

with a chance of winning a starter pack

worth £159.95, enter before the end of

the 11th of November. Reasons you

might want to use a FreeStyle Libre:

1. Convenient: A small sensor

automatically measures and continuously

stores glucose readings day and night.

2. Discreet: Glucose readings with a

painless 1-second scan even through


3. Easy: Swim, shower or exercise - the

FreeStyle Libre system is designed to be

water-resistant and worn while bathing,

showering, swimming and exercising.

4. User-friendly: With every scan you

get your current glucose reading, the last

8 hours of glucose data, and an arrow

shows where your glucose is heading.*

You can try the FreeStyle Libre flash

glucose monitoring system with a starter

pack which includes a reader and two

FreeStyle Libre sensors. To enter our

competition to win one starter pack worth

£159.95 CLICK HERE.

*A finger prick test using a blood glucose

meter is required during times of rapidly changing

glucose levels when interstitial fluid glucose levels

may not accurately reflect blood glucose levels,

or if hypoglycemia or impending hypoglycemia

is reported or the symptoms do not match the

system readings. Scanning the sensor to obtain

glucose values does not require lancets. For

a complete glycemic picture, scan once every

8 hours.The reader can capture data from the

sensor when it is within 1cm to 4cm of the sensor.

Sensor is water-resistant in up to 1 metre (3 feet)

of water for a maximum of 30 minutes.



Researchers in an international study have

uncovered new genetic evidence of how

the benefits of the world's most commonly

used Type 2 diabetes drug may vary

between individuals. Metformin, the drug

used by hundreds of millions of people

with Type 2 diabetes worldwide, has been

in use for more than 50 years. It has been

shown to protect against heart disease,

eye and kidney disease in people with Type

2 diabetes, and has also been shown to

have benefits against cancer. Metformin

is also undergoing new clinical trials to

determine if it can promote health aging.

It has been known for some time that

Metformin works better in some people

than others but the reasons for this have

not been understood. Now research led by

the University of Dundee and University of

California, San Francisco has identified a

genetic variant (a change in the DNA code

for a particular gene) that alters how well

metformin works. Researchers found that

overweight people carrying two copies

of a genetic variant responded so much

better to metformin that it was equivalent to

receiving an extra 550mg of the drug. They

say their findings represent a significant

step towards personalised, targeted

therapy in the treatment of Type 2 diabetes.

The research has been funded by

Wellcome, Diabetes UK and the National

Institutes of Health in the US and is

published in the journal Nature Genetics.

The Metformin Genetics Consortium

identified a genetic variant in the gene

encoding the glucose transporter GLUT2,

a protein that plays an important role in

transporting glucose inside the body. They

showed that those people who carried this

variant had reduced levels of GLUT2 in the

liver and other tissues resulting in a defect in

how the body handles glucose. Metformin

acted to specifically reverse this deficiency

resulting in a better response to metformin

in people carrying this gene variant.

Dr Elizabeth Robertson, Director of

Research at Diabetes UK, said, "This

study sheds important light on why

people with Type 2 diabetes respond

differently to metformin. Altogether, this

research represents an exciting step

towards personalised therapy for Type

2 diabetes, moving away from a 'one

size fits all' approach to ensure people

receive the best treatment possible. We're

very pleased to see research funded by

Diabetes UK moving the field of Type 2

diabetes treatment forwards."


People with diabetes should have their

feet checked at least annually and should

also be taught how to look after their feet

themselves. The charity IDDT wants to

help reduce the risks of foot damage so it

has published a new, free booklet called

Diabetes - Looking After Your Feet. It is

designed to help people to look after their

feet by providing information on what to

look for and giving advice as to when to

seek treatment to keep their feet healthy.

For a copy, email:



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