Desang diabetes magazine diabetes news



Hit West End musical Charlie and the

Chocolate Factory has removed a line that

said 'eating chocolate causes diabetes,'

after a mother campaigned for its

change. London resident Nathalie Bristow

contacted its production company after

taking her 8-year-old daughter Laura -

who has T1 diabetes - to see the show.

Mrs Bristow said: "My family love


The U.S. Food and Drug Administration

(FDA) has expanded the approved use for

Lucentis (ranibizumab injection) 0.3 mg to

treat diabetic retinopathy (DR) in patients

with diabetic macular oedema (DMO).

Diabetic retinopathy is the most common

diabetic eye disease In 2008, 33% of

adults with diabetes in the US aged 40

years or older had some form of DR.

Lucentis is administered by a physician

as an injection into the eye once a month.

It is intended to be used along with

appropriate interventions to control blood

sugar, blood pressure and cholesterol.

The drug's safety and efficacy to treat DR

with DMO were established in two clinical

studies involving 759 participants who

were treated and followed for three years.

In the two studies, participants being

treated with Lucentis showed significant

improvement in the severity of their DR at

two years compared to patients who did

not receive an injection.

The FDA granted Lucentis for DR with

DMO 'breakthrough therapy' designation

based on preliminary clinical evidence

indicating the drug may demonstrate a

substantial improvement over available

therapies for patients with serious or lifethreatening

conditions. The FDA previously

had approved Lucentis to treat DME and

macular edema secondary to retinal vein

occlusions, both of which cause fluid to

leak into the macula resulting in blurred

vision. Lucentis also is approved to treat

wet (neovascular) age-related macular

degeneration (AMD), a condition in which

abnormal blood vessels grow and leak

fluid into the macula.

Lucentis is marketed by South San

Francisco, California-based Genentech,

a subsidiary of Roche.




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the theatre, so were deeply upset and

offended when we heard the line about

how children will get diabetes if they

eat too much chocolate. We nearly left.

Thousands of people - including parents

and children - see the show every day. I

would hate for this to have a damaging

effect on the perception of Type 1

diabetes. The producers could not have

been more helpful though - a big theatre

listened to us and we made a difference."


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