diabetes news, Dr John Fossey, glucose

NEWS

SMART THINKING

David Gregory-Kumar, the BBC's Science, Environment & Rural

Affairs Correspondent reported on how 'smart' insulin could

drastically reduce the number of injections diabetics would need to

take, saying: "For people with Type 1 diabetes much of their time

is spent controlling the disease by testing their blood and injecting

insulin. For young people with diabetes it's particularly complicated,

but even old hands sometimes just experience 'diabetes burnout',

where it all seems totally overwhelming. So the idea of 'smart'

insulin, a way to deliver this essential drug without all the testing

and injections is hugely attractive and now scientists in Birmingham

are starting work on a delivery system that might allow them do

just that."

At the end of 2016, Gregory-Kumar visited Dr John Fossey at

Birmingham University who had just secured funding from JDRF for

research into the smart insulin concept. "Dr Fossey and his team

have used some very clever chemistry to create a gel that only

dissolves in the presence of glucose. Indeed he showed me how

his gel disappears in a glucose solution while just sitting there in

ordinary water. The idea is to load up the gel with insulin, then as the

glucose levels rise in someone with diabetes, the gel dissolves and

the insulin is released into their system. It would be an alternative to

the current methods where a diabetic has to carry out blood tests,

work out the right dose of insulin and then inject it. With the gel, the

chemistry does all this automatically."

Such gels are being researched in other laboratories around

the world, but Dr Fossey believes his gel has unique chemistry that

makes it the best prospect for this sort of approach. It is very early

stages in the research. After they've worked out the chemistry, the

project will then move into a biology lab and then eventually, in

about 10 years, there might see clinical trials in humans if it all goes

well. You can download initial research results HERE.

The research was also reported on by The Telegraph, by

Science Editor Sarah Knapton, who noted, "Dr Fossey explained

that his proposal was to take gel molecules and build a container

for insulin, which will break open when it comes across glucose

and deliver its cargo. The patient could be injected with these

containers, say once a week, and they would slowly degrade in

the presence of glucose to keep blood sugar at a constant level."

Sarah Johnson, Director of Mission at JDRF added, "We

are pleased to be funding Dr Fossey's work. This early stage of

research could lay the foundations for a glucose responsive insulin

that would be injected once a day, or even a week, and respond

to glucose levels just like a healthy pancreas. This would be a life

changing treatment for all those living with Type 1 diabetes."

To see the BBC report click HERE.

FASTER INSULIN

IN THE LOOP

Reported by staff writers on Diabetes Daily, a US-based

website in February 2017, the law firm Hagens Berman,

is a very successful consumer rights firm, is representing

people living with diabetes in a class action suit against

the 'Big Three' insulin makers Eli Lilly, Novo Nordisk, and

Sanofi which have been accused of unfairly raising their

prices and thus monopolizing the insulin market by the

plaintiffs in the case: people with Type 1 diabetes.

Law suit.

INSULIN LAW SUIT

Faster insulin action is associated with improved glycemic

outcomes during closed-loop insulin delivery and sensoraugmented pump therapy in adults with Type

1 diabetes

according to a new study. Faster insulin in pumps.

APPLE'S SENSORS

As reported by Reuters, Apple has hired a team of

biomedical engineers as part of an initiative, initially

envisioned by late Apple co-founder Steve Jobs, to

develop sensors to treat diabetes. The news comes at

the time when the line between pharmaceuticals and

technology is blurring as companies are joining forces

to tackle chronic diseases using high-tech devices that

combine biology, software and hardware, thereby jumpstarting a

novel field of medicine called bioelectronics.

Apple Sensors.

A BIG INTERVIEW

Cellnovo Group and digital health company TypeZero

Technologies have completed a worldwide commercial

license agreement for the integration and the

commercialization of TypeZero's Artificial Pancreas (AP)

technology into Cellnovo's mobile diabetes management

systems. T Integration efforts are currently underway

with a product launch expected in 2018. TypeZero's AP

software, known as inControl AP, will be incorporated

directly into Cellnovo's Bluetooth-enabled insulin pump.

NEWS BITES

Index

  1. Desang diabetes magazine diabetes information
  2. Abbott Freestyle Libre, Flash Glucose Monitoring, blood testing without lancets
  3. Desang diabetes magazine diabetes information, Sue Marshall
  4. diabetes news, novo nordisk insulin fiasp
  5. diabetes news, Medtronic, Medtronic Guardian Connect, BiAP
  6. diabetes news, Dr John Fossey, glucose
  7. Novo Nordisk diabetes mealtime management
  8. diabetes care, pocket medic, Kimberley Littlemore, Type 2 diabetes
  9. diabetes care, pocket medic, Kimberley Littlemore, Type 2 diabetes
  10. Ten Acre crisps, Jacob's Crackers
  11. A1C self check, HbA1c, Sweet Freedom
  12. Jean Cazels photography, British sandwiches, Heinz Seriously good mayo
  13. Ascensia Contour Diabetes blood test meters
  14. Accu-Chek Mobile blood glucose system
  15. Accu-Chek Mobile blood glucose system
  16. Redring tea survey, The Tea Terrace,
  17. Ecoffee, Costa Coffee
  18. Sue Marshall diabetes Professor Nick Oliver Imperial College London
  19. Professor Nick Oliver Imperial College London, BiAP, bio-inspired artificial pancreas, ABC4D, Chris
  20. Dr Philip Toleikis, Sernova, Cell Pouch technology, islet cell transplants, glucose responsive techn
  21. Dr Philip Toleikis, Sernova, Cell Pouch technology, islet cell transplants, glucose responsive techn
  22. Making Carbs Count, greek yoghurt
  23. Making Carbs Count, greek yoghurt
  24. Accu-Chek Insight insulin pump, making carbs count
  25. Accu-Chek Insight insulin pump
  26. Free diabetes magazine, Desang diabetes magazine,

Related Issues