23
KIT
Many clinicians
regarded
hypoglycaemia
as an irritating
inconvenience
that interfered
with clinical
management of
diabetes ~
Dr Brian Frier
could impact, such as mood, fear
of lows, sleep quality, cognitive
functioning, and more. Each
person was also given a Fitbit to
determine whether low blood sugar
episodes were happening while
they were awake or asleep. The app
then assessed the effects of both
symptomatic and asymptomatic
episodes of hypoglycaemia on a
person's daily functioning.
Over the course of 10 weeks,
researchers collected close to one
million hours of continuous glucose
monitor (CGM) data, equating to
roughly 100 years of patient data.
The time in range of Type 1 and Type
2 diabetes participants was fairly
close (61% and 65%, respectively).
Interestingly, Choudhary said
around 65% of sensor-detected
hypoglycaemic events were
asymptomatic.
Hunger games
Using CGM, it turns out that most
hypoglycaemic episodes were not
detected by participants. Also,
almost half the episodes participants
reported as hypoglycaemia actually
weren't, with the most common
symptom thought to be related to
low blood sugar being hunger. This
data offers convincing evidence of
the need for CGM, especially for
people using insulin - regardless of
whether they think they are aware of
hypoglycaemia episodes or not.
Researchers like Choudhary
hope the new data will not only
offer a better understanding of
the differences and impacts of
asymptomatic and symptomatic
hypoglycemia, but also help push
forward the overall mission of the
Hypo-RESOLVE project: reducing
the burden and consequences of low
blood sugar episodes for people with
diabetes.
Another small 2023 study
concluded that together with CGM,
the Hypo-METRICS app, while
created for research purposes, could
have clinical value for monitoring
and assessing awareness of low blood
sugar symptoms and the impact
these episodes have on a person's
day-to-day life.
Frier said it's still too early to
judge the overall success of HypoRESOLVE
in advancing the overall
scientific knowledge of changes
in blood glucose, but that it's
"reasonable to expect that some
of the research outcomes will be
translated into clinical benefits for
diabetes care."
To read the original article
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