30
KIT
reduce episodes of hypoglycaemia
and achieve good glycaemic control
for prepubescent children (21
children aged 6 to 12 years) with
Type 1 diabetes in real-life conditions
(i.e. the trial was not undertaken in
a hospital environment but in the
home and school).
Medscape French Edition
questioned endocrinologist and
diabetes specialist and conference
chair Eric Renard, MD, PhD, head of
the Department of Endocrinology
and Diabetes at Lapeyronie Hospital
in Montpellier, about these results,
especially those from adolescents
with poorly controlled diabetes.
The expert was not surprised at
the findings from the study. Renard
said, "We have already seen studies
in which those patients who had
the most poorly controlled diabetes
at the start were the ones who
improved the most with the closedloop system, by
at least 20% in terms
of time in target. These findings
resonate with what I see in my
clinic. In my experience, these young
adolescents, who neglected their
diabetes when they had no devices
to help control it, when they had to
inject themselves, et cetera... well,
they're just not the same people
when they're put on a closedloop system."
He added, "They rise to the
challenge, and for the first time,
they succeed without making a huge
effort, since the algorithm does what
they weren't doing. It's astonishing
to see near-total engagement in
these young people when explaining
the technology to them and saying,
'Let's give it a go.' These are the very
same youngsters who didn't want to
hear about their diabetes in the past.
They are delighted to be once again
involved in managing their condition."
Renard recommends keeping
an open mind when considering
treatment options for young patients
with poorly controlled Type 1
diabetes, "When young people have
very poorly controlled diabetes,
they risk having cardiovascular
complications and damaging their
retinas and kidneys," he said. "If we
can get them from 25% to 45% time
in target, even if that hasn't been
easy to achieve, this will help save
their blood vessels! The only thing
we have to be careful of is that we
don't set up a closed-loop system in
someone who doesn't want one. But,
if it can manage to spark the interest
of a young patient, in most cases,
it's beneficial."
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By Aude Lecrubier, April 2023, translated from the Medscape French edition*.